Born in Funchal, Portugal, in 1962, Regina Aires studied with Lídia Carvalho at the Music Conservatoire in Lisbon, where she graduated in 1981. At the same time she had chamber music and violin interpretation classes with François Broos and Alberto Lysy, having been awarded the second prize at the Braga National Competition in 1978. She continued her studies in Paris with Gérard Poulet and Annie Jodry on a scholarship from the Gulbenkian Foundation.
Regina Aires has been a member of several international orchestras, such as the European Countries Orchestra and the Youth Orchestra of the Mediterranean Countries where she was assistant concert master, and had the opportunity to work with such remarkable conductors as Jean-Jacques Werner, Mario Venzago and Michel Tabachnik.
She has given recitals in Paris and all over Portugal, having performed as a soloist with the Orquestra D. Fernando. She has also been a member of several Portuguese orchestras, namely the Orquestra da Radiodifusão Portuguesa , the Orquestra Gulbenkian , Regie Sinfonia and the Orquestra do Teatro Nacional de São Carlos. Since 1993 she has been a member of the Orquestra Sinfónica Portuguesa. Between 1986 and 1988 Regina Aires was a teacher at the National School of Music in Lisbon, Portugal. She is a founding member of the Lacerda String Quartet since 1990.